The renal clearance of hydrochlorothiazide in people with normal renal perform is 285mL/min. Individuals using a creatinine clearance of 31-80mL/min have a mean hydroxychlorothiazide renal clearance of 75mL/min, and individuals by using a creatinine clearance of ≤30mL/min have a median hydroxychlorothiazide renal clearance of 17mL/min.Irbesartan
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